Israel and Iran have opened a new chapter in their long history of conflict. Israel launched a major attack with strikes early Friday that set off explosions in the Iranian capital of Tehran.

It’s too soon to tell how exactly the current wave of Israeli strikes could transform the region, but one thing is clear: Israel’s actions have fundamentally reshaped the security landscape of the Middle East.

Iran conflict could open opportunities for Russia to possibly become a power broker to help end the confrontation.

The "America First" president praised his foreign policy record on Sunday while urging a deal between Iran and Israel amid escalating strikes.

Iran launched retaliatory strikes on Israel after Netanyahu said Israel began an operation to push back on Iran's "threat to Israel's very survival."

Sirens sounded in Israel as Iran launched dozens of ballistic missiles in retaliation for Israel's strikes on its nuclear facilities.

Iran has already developed a range of options to retaliate for strikes from Israel or the United States, potentially plunging the region into deeper turmoil

Senate Minority Leader Chuck Schumer is the only one of the top four congressional leaders not to react so far