In an effort to reveal the inner workings of a protein that serves as a cell's damage detection system, scientists at Johns ...

H5_fold-0_Chantal, H5_fold-0_Elsa, H6_fold-C_Rei, H6_fold-Z_Gogy, H6_fold-U_Nomur, and H7_fold-K_Mussoc are presented. For each de novo designed protein, the computational model is shown on the left, ...

Efforts to unlock the mysteries of proteins, building blocks of life, have earned three scientists the 2024 Nobel Prize in chemistry. The prize goes to David Baker “for computational protein design,” ...

The international competition to predict the three-dimensional (3D) structures of 43 proteins, using computational tools, was intense. Of the 123 groups competing in the fourth Critical Assessment of ...

As bispecifics, ADCs, protein degraders, and AI-designed mini-proteins move into the clinic, discovery teams face a new ...

The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion. While healthy transthyretin moves hormones through blood and spinal fluid, misfolded ...

UCLA scientists have characterized the structure and function of a key survival protein in breast cancer cells that helps ...

Today (September 21), the Lasker Foundation announced this year’s award winners. John Jumper, a computational biologist at DeepMind, and Demis Hassabis, cofounder and CEO at DeepMind, were awarded the ...

A multi-institute team led by St. Jude Children's Research Hospital and UT Southwestern Medical Center investigators ...