San Francisco 49ers defensive end Yetur Gross-Matos underwent knee surgery and will miss several weeks. More news: Bengals ...

Kyler Murray had a long touchdown run in the first quarter and rallied Arizona with two fourth-quarter scoring drives in the ...

The San Francisco 49ers (2-2) meet a fellow NFC West foe when they host the Arizona Cardinals (1-3) on Sunday, October 6, ...

The record-breaking heat for a San Francisco 49ers game at Levi’s Stadium has sent fans at the game down to the concourses.

The 49ers average just 0.7 fewer points per game (25.8) than the Cardinals give up (26.5). San Francisco racks up 413.3 yards ...

Arizona shuts down San Francisco in second half to stage late rally after trailing by as much as 13 points on the road.

The 49ers collect 413.3 yards per game, 58.5 more yards than the 354.8 the Cardinals allow per contest. San Francisco rushes ...

The 49ers just blew another 10-point fourth quarter lead and lost 24-23 to the Arizona Cardinals. Now the 49ers are 2-3. Here ...

The high of Deommodore Lenoir’s 61-yard return of a blocked field goal was followed by an injury that put place kicker Jake ...

The 49ers along with their fans are going to be sweating it out in their red and gold for Sunday's game against the Cardinals ...

A matchup with the banged-up, struggling New England Patriots was just what the San Francisco 49ers needed following ...

The Charlotte 49ers faced one of their new American Athletic Conference opponents in just the second meeting between the ...