The San Francisco 49ers were thought to be among the favorites to represent the NFC in the Super Bowl for a second straight year, but they haven't ...

It ended with him driving the Arizona Cardinals into field goal position and then becoming a spectator watching his team's fill-in kicker and defense come through at the end. Both delivered with Chad ...

After swapping his cleats for a microphone, the spotlight during Sunday's game between the San Francisco 49ers and Arizona ...

The home run run plays have been missing from the 49ers’ offense so far this season. That one evaded Guerendo on Sunday, but ...

Isaac Guerendo only has six career NFL carries, but the rookie running back is making a strong impression on his 49ers ...

SANTA CLARA -- The 49ers are extremely hopeful about rookie running back Isaac ... That's a good feeling, right on the emblem ...

SportsLine's model simulated Arizona Cardinals vs. San Francisco 49ers 10,000 times and made its Week 5 NFL picks, ...

The San Francisco 49ers activate Kalia Davis, delay Ricky Pearsall's return as team manages injuries and roster moves.

An Aussie had a career day, and the rookie throwers are starting to make their mark as the NFL reached week five.

SANTA CLARA -- Jauan Jennings' agent messed up. This offseason, Jennings signed a two-year, $15 million extension with the 49ers. At the time it was a significant raise for Jennings, a former ...