But the first series — a two-play, 72-yard touchdown drive, saw Campbell burned on a chunk-yard pass and then a 50-yard ...

After spending big money to find a competent defensive end opposite Nick Bosa, the Niners might have found the right man in a ...

SANTA CLARA - Five years after going through his own cancer scare, Trent Williams decided it was time to get involved in the ...

San Francisco 49ers running back Jordan Mason enters high gear on a 34-yard rush vs. Arizona Cardinals. Los Angeles Rams quarterback Matthew Stafford rips a 24-yard dart to Rams wide receiver Tutu ...

Thankfully for the red and gold, the defense stepped up and picked off Darnold just four plays later. A few plays after letting out a sigh of relief, 49ers quarterback Brock Purdy threw an ...

One of the major keys for San Francisco will be the intensity of the team’s pass rush. In their Week One win over the New York Jets, the 49ers sacked quarterback Aaron Rodgers just once ...

The 49ers have the perfect solution to their linebacker woes, of course, in Dre Greenlaw. But they won’t rush his return from a Feb. 11 ruptured Achilles tendon. The Nov. 10 game in Tampa Bay ...

The San Francisco 49ers will be without star running back Christian McCaffrey for a while. The 49ers are placing McCaffrey on injured reserve, a person familiar with the situation told USA TODAY ...

McCaffrey is a do-it-all back that gives defenses fits. The 49ers have talent all over their offense but it starts with McCaffrey. He rushed for 1,459 yards and 14 touchdowns last season and had ...

No consistent pass rush (three sacks, giving Haason Reddick ... New York Jets defensive end Micheal Clemons #72 tackles San Francisco 49ers wide receiver Deebo Samuel Sr. #1 during the second ...