The final structure of the adenosine A2A receptor was examined in the study. The yellow spheres are sulfur atoms, the blue spheres are water molecules, and the blue lines represent the lipid membrane.

Both the injectable and oral forms of semaglutide, a glucagon-like peptide-1 receptor agonist, have gained recent attention ...

The long-running dispute dates back to 2018, when Hospira filed for approval of its generic of Lexiscan, an A2A adenosine receptor agonist used alongside radionuclide, myocardial perfusion imaging ...

Dopamine’s effects in the brain are mediated by postsynaptic D1 and D2 receptors. Adenosine A1 and A2A receptors are uniquely positioned to counteract the excessive stimulation of dopamine receptors ...

KW-6356 has a higher affinity and selectivity for adenosine A2A receptors, leading Kyowa Kiri to speculate that it could obtain approval for a wider group of Parkinson's patients than Nourianz.

These specialized T-cell express receptors that recognize specific antigens ... the investigators found that the adenosine A2A receptor (A2AR) signaling pathway coordinates with the GSH-GPX4 ...

focusing on G protein-coupled receptors (GPCRs), which are vital for cell signaling and drug discovery. The researchers employed computational tools to re-engineer the adenosine A2A receptor and ...

Portage Biotech (PRTG) presented new preclinical data for PORT-7, a selective Adenosine A2B receptor inhibitor. The new data demonstrate both ...