Alpha-1-antitrypsin is a so-called protease inhibitor, a type of enzyme inhibitor. It is produced in the liver but exerts its effects in the lungs, where it regulates immune cell activity. This ...

Researchers have identified alpha-1 antitrypsin deficiency (AATD) as a genetic condition that raises your risk of developing COPD. People with AATD have lungs that are more sensitive to damage ...

To the point. Hereditary disease alpha-1-antitrypsin deficiency: Researchers have discovered why some patients remain healthy despite a genetic defect, while others develop severe liver fibrosis Deep ...

The global alpha-1 antitrypsin deficiency (AATD) market is expanding, driven by advances in diagnosis, treatment, and growing awareness. Key players like Grifols, CSL Behring, and Pfizer lead ...

Researchers report on the safety of a gene therapy to treat the common autosomal recessive hereditary disorder alpha 1-antitrypsin (AAT) deficiency in a new article in Human Gene Therapy.

The risk for those who were both alpha-1 antitrypsin deficiency carriers and current smokers, relative to never smokers who lacked the genetic defect, was elevated 20 times.

According to Market.us, the global alpha-1 antitrypsin deficiency augmentation therapy market growth is driven by the increase in the prevalence of Genetic and Respiratory diseases and modern ...

Newer Treatments In Alpha-1 Antitrypsin Deficiency: $2.5 Billion/Year Market Size By 2032 Mar. 14, 2024 5:34 PM ET MREO , WVE , KRRO , KRYS , TAK , TKPHF 3 Comments 2 Likes Bhavneesh Sharma ...

Alpha-1 antitrypsin deficiency (AATD) is a genetic disorder characterized by the misfolding and accumulation of the mutant variant of alpha-1 antitrypsin (AAT) within hepatocytes, which limits its ...

Patients with alpha-1 antitrypsin deficiency (AATD) faced an increased risk for cardiovascular disease based on aortic pulse wave velocity. In AATD, this measure was linked to proteinase 3 activity.

04/17/2025 16:04 Alpha-1 antitrypsin deficiency: What protects the one – and not the other? Dr. Christiane Menzfeld Öffentlichkeitsarbeit Max-Planck-Institut für Biochemie. As part of an ...