Furthermore, current knowledge of the signals regulating antibody glycosylation and how individual antibody glycoforms could be used to optimize current treatment approaches will be discussed.

GEN: Accurate glycosylation is essential for proper functioning of monoclonal antibodies (mAbs) generated in vitro. What are the advantages and disadvantages of using engineered bacterial or yeast ...

This process, called glycosylation, facilitates the antibody's ability to bind to other immune cells, thereby strengthening the body's defensive reaction. Characteristic sugar structures that are ...

Concerns regarding glycosylation and safety originated during the early days of therapeutic antibodies, when murine proteins carrying mouse glycans were discovered to be immunogenic. Now that ...

This research, published online January 22 and in the February issue of the journal Nature Biotechnology, demonstrates that antibodies with human sugar structures (glycosylation) can be produced ...

"If the process of antibody glycosylation is defective, then the consequences can be severe," explains Benedetti. Several diseases, including diabetes, autoimmune diseases such as lupus and cancer ...

The glycosylation pattern detected in cells from ... The preserved rates of immunoglobulin production and functional antibody responses to bacterial antigens that we observed, together with ...

EWING, N.J., May 31, 2017 /PRNewswire/ -- Cell-Ess® media from Essential Pharmaceuticals, LLC has been shown to increase antibody titer and improve glycosylation in a new bioproduction study.

EWING, N.J., June 13, 2017 /PRNewswire/ -- Essential Pharmaceuticals, LLC Chief Science Officer, Dr. Adam Elhofy, will be discussing mechanisms to increase antibody titer and present new data on ...

Elina is a PhD candidate at the University of Toronto studying the regulation of microbial shikimate dehydrogenase enzymes. Elina joined the Creative Services Team as an intern and assists with ...

Bleiholder's team confirmed that structural variations among antibody populations are not influenced by glycosylation—a ...