Supporting the relevance of studying hallucinogens to understand schizophrenia, however, is the observation that the serotonin 2A receptor also interacts with atypical antipsychotic medications ...

such as the 5-HT 1A receptor, are considered to mediate the ability of antipsychotic drugs to enhance cognition. On the other hand, treatment with some atypical agents, such as risperidone ...

I know first-hand why people go off antipsychotics, and why it is hard to stay on them. I went off of them twice on my own and paid dearly for it. I know many others who go through similar issues ...

Current antipsychotic medications block dopamine receptors to help manage hallucinations, delusions, and other symptoms of schizophrenia. But those drugs can cause serious motor and metabolic side ...

Vanda Pharmaceuticals Inc. (Vanda) (NASDAQ: VNDA) today announced that a New Drug Application (NDA) was submitted to the U.S.

which suppresses side-effects associated with antipsychotics. Developed by Karuna Therapeutics, now part of Bristol Myers Squibb (BMS), it works by targeting receptors in the brain that modulate ...

Previous attempts to selectively modulate muscarinic receptors by targeting the acetylcholine ... had activity in rodent models predictive of antipsychotic efficacy. It attenuated conditioned ...

While tardive dyskinesia is most often caused by sustained exposure to antipsychotics, any drug that significantly blocks dopamine receptors can be a culprit, said Demian Rose, MD, PhD ...

Although antipsychotics were developed to treat schizophrenia, newer ones are sometimes used to treat depression that has not been relieved by antidepressants or other treatments. Depression is a ...

Distinct pharmacologic profiles, especially actions on 5-hydroxytryptamine (5-HT) receptor subtypes, may contribute to the advantage of atypical antipsychotics in terms of adverse effects.