Brain-derived neurotrophic factor (BDNF) has an important role in supporting neuronal survival, which has encouraged studies of its therapeutic potential for neurodegenerative disorders such as ...

Their findings, published in Nature Neuroscience, unveiled the existence of astrocytic ensembles, specialized astrocyte subsets that appear to be active during reward-driven behaviors.

Astrocytes are the largest and most prevalent type of glial cell in the central nervous system. Astrocytes contribute to formation of the blood–brain barrier, participate in the maintenance of ...

Figure: Solution structure of human MANF protein. PDB ID: 2KVD [7]. Cerebral dopamine neurotrophic factor (CDNF) and mesencephalic astrocyte derived neurotrophic factor (MANF) form an evolutionary ...

Get Instant Summarized Text (Gist) The study identifies distinct subtypes of white matter astrocytes, including a unique type with regenerative potential. Using advanced sequencing techniques ...