Moreover, it enters the brain tissue and resident cells through blood vessels by penetrating the tightly organized blood–brain barrier. The dNP2-conjugated cytoplasmic domain of cytotoxic T ...

When L6-F4-2 replaced the missing Norrin protein, the blood-retinal layer ... Andrea Califano, Wen-Chen Yeh, Yang Li, Calvin J. Kuo. Therapeutic blood-brain barrier modulation and stroke ...

Scientists have long known that the Alzheimer's brain often features abnormal plaques and tangles, and recent studies have ...

Scientists have been focusing on frizzled, a protein receptor that initiates the WNT pathway, for blood-brain barrier therapies since mouse mutations in the frizzled gene cause blood-brain barrier ...

Mar 19, 2024: Gold nanocatalysts cross blood-brain barrier aided by unique protein corona composition (Nanowerk Spotlight) The blood-brain barrier, a tightly regulated interface between the ...

Fat-soluble substances can get through the blood-brain barrier if crafted correctly, carrying with them a mix of elements such as proteins, antibodies, or mRNA. And it is that mRNA that has the ...

Other molecules, like sugars, can be escorted past the tight chain via proteins. But large molecules, including many drugs, ... and they’ll cross the blood-brain barrier,” Mirkin says.

Getting drugs to the brain is difficult. The very thing designed to protect the brain's environment — the blood-brain barrier (BBB), tightly packed cells that prevent most substances from ...

It may cause lung problems that affect blood flow or leaks in the blood-brain barrier. ... He is skeptical about the blood clotting proteins’ role in long COVID, however.

In these brain conditions, it can be hard to tell which factors cause the disease and which are just side effects of the condition. The researchers now plan to study blood samples from donors to ...

To get a broader idea of the impact of these proteins, Wei-Shi Liu at Fudan University in China and his colleagues analysed MRI brain scan data from nearly 11,000 adults from the UK Biobank ...

There's a bouncer in everyone: The blood-brain barrier, a layer of cells between blood vessels and the rest of the brain, kicks out toxins, pathogens and other undesirables that can sabotage the ...