In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur ...

UNC researchers discovered how a key step in cell signaling works by showing exactly how G proteins detach from receptors ...

In their new study, the LJI scientists are the first to show that GPR25 is induced by a signaling molecule called TGF-β.

Direct contact with ESCC cells leads mesenchymal stem cells (MSCs) to become cancer-associated fibroblast (CAF)-like cells, which secrete periostin and activate the Akt and extracellular ...

Cells use various signaling molecules to regulate the nervous, immune, and vascular systems. Among these, nitric oxide (NO) and ammonia (NH₃) play important roles, but their chemical instability and ...

Researchers at Tulane University, with a team of colleagues from eight other universities, have discovered a new nerve cell signaling mechanism that could transform our understanding of pain and lead ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, No. 32 (August 10, 2021), pp. 1-10 (10 pages) Male and female animals exhibit differences in infection ...

Specified intestinal epithelial cells reprogram and contribute to the regeneration and renewal of the epithelium upon injury. Mutations that deregulate such renewal processes may contribute to ...