From these findings, it seems that many drugs that inhibit fusion do so by removing cholesterol from the plasma membrane. Since this involves the plasma membrane of the virus, containing the spike ...

Cholesterols help in cell signalling by assisting in the formation of lipid rafts in the plasma membrane. Cholesterol in the myelin sheaths – The nerve cells are covered with a protective layer ...

Cholesterol is one of the key molecules found in biomembranes, complex structures composed of proteins and lipids. It plays a crucial role in organizing the membrane and influencing the behavior ...

Mihailescu says the findings hint that cholesterol may have profound consequences for the membrane's gatekeeper proteins, which are very sensitive to their environment. "The membrane and its ...

In support of this, the scientists also found that depletion of Niemann-Pick C1 protein (NPC1)—which transports cholesterol to the plasma membrane—opened the cytosolic floodgates for tau. Mutations in ...

Cholesterol is instrumental in HIV's ability to infiltrate cells, and removing this fatty material from a cell's membrane blocks infection, according to a Johns Hopkins study reported in the July ...

Membrane fusion is an important reaction ... Published in the Biophysical Journal, their findings show that pore dynamics are regulated by cholesterol, the absence of which leads to shorter “kiss and ...

Exchange of material and information at the level of individual cells requires transport and signaling at the level of the plasma membrane enclosing the cell. Studying mechanisms at such tiny ...

Mihailescu says the findings hint that cholesterol may have profound consequences for the membrane’s gatekeeper proteins, which are very sensitive to their environment. “The membrane and its ...