Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can ...

A team led by Professor Kazuhiro Maeshima of the National Institute of Genetics (ROIS) and SOKENDAI in Japan has developed a ...

The Whitehouse lab is broadly interested in understanding how chromatin functions in the regulation of cellular processes such as DNA replication, gene transcription and epigenetics. We focus on ...

The interdisciplinary and cross-institutional team employed a variety of methods to untangle Exportin-1's specific functions in budding yeast, including single molecule tracking, chromatin ...

Jones’ team obtained chromatin immunoprecipitated DNA fragments to which the signal transducer and activator of transcription 1 (Stat1), a transcription factor with a well characterized function in ...

Dr. Arimura’s insights will help scientists better understand how chromatin functions, how it’s regulated, and what goes wrong in diseases like cancer.

The Dere lab specializes in kidney cancer and VHL (von Hippel Lindau) disease focused on understand fundamental aspects of how non-chromatin functions of chromatin modifiers contribute to oncogenesis.

How the cell achieves this feat remains largely unknown. Now, for the first time, EMBL scientists have directly observed this process in high resolution under the microscope using a new chromatin ...

A novel technique to visualize gene-active and gene-repressive DNA regions in living cells, developed by a ...