More information: Elena Grossi et al, The SWI/SNF PBAF complex facilitates REST occupancy at repressive chromatin, Molecular Cell (2025). DOI: 10.1016/j.molcel.2025.03.026 Provided by The Mount ...

To better understand how chromatin remodeling works, scientists at St. Jude Children's Research Hospital used cryo-electron microscopy (cryo-EM) to obtain fine structural details of a human ...

Chromatin remodelers play a key role in regulating access to DNA (which is packed within the cell into chromatin), hence allowing other DNA-interacting processes to take place. Although mutations ...

This Collection welcomes original research into chromatin and cancer, including studies exploring the mechanisms by which chromatin modifiers and remodelers, ...