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Phase I Study of Paclitaxel Given by Seven-Week Continuous Infusion Concurrent With Radiation Therapy for Locally Advanced Squamous Cell Carcinoma of the Head and Neck

PURPOSE: Paclitaxel is one of the most active agents for squamous cell carcinoma of the head and neck (SCCHN) and an in vitro radiosensitizer. The dose-response relationship for paclitaxel may depend ...
Nature

Blood vessel density correlates with the effects of targeted intra-arterial carboplatin infusion with concurrent radiotherapy for squamous cell carcinomas of the oral cavity ...

Inbred female Japanese white rabbits weighing 3–4 kg were used throughout the experiment. The animals were anaesthetised via the auricular vein using pentobarbital sodium (1 mg kg −1), and then VX2 ...
Nature

Concurrent blinatumomab and donor lymphocyte infusions for treatment of relapsed pre-B-cell ALL after allogeneic hematopoietic cell transplant

Patient 1 relapsed 4.5 months after a matched sibling donor transplant, treated with three cycles of salvage chemotherapy with two DLI with persistent marrow disease (7% blasts) before starting ...