Intrinsically disordered proteins (IDPs) can dynamically change their conformations depending on their external environment and can, therefore, bind to different compounds. However, they are ...

Through X-ray crystallography methods, which initially involve purification of the proteins, Sondek's team has determined the molecular structure of a Rho family G protein bound to its activator ...

Crystal Structure Of Protein Interaction Could Lead To New Drugs Against Cancer Date: December 11, 2000 Source: University Of North Carolina School Of Medicine ...

Rhodopsin is a light-activated G-protein-coupled receptor. The structure of its ligand-free state at 2.9 Å resolution was reported recently. This paper describes a similar resolution crystal ...

The new crystal structure shows exactly how the individual dynamin proteins can line up to form a helix, and then move by ratcheting alongside each other. It also shows that part of the protein ...

Knowing the crystal structure of this "doorway" protein, says Fraser, is key to finding helpful drugs to stop coronavirus and influenza viruses, ...

Once such structures are formed, the faith of the system is set. Dr. Alexander Van Driessche explains: "By analyzing and understanding the differences in structure of the various nuclei, we ...

Background: Antifreeze proteins bind to ice crystals and inhibit their growth. Results: The crystal structure of a potent beetle antifreeze protein was determined by direct methods. Conclusion: ...

Open-sourcing of protein-structure software is already paying off The big trade-off is between computational intensity and the size of the complex. John Timmer – Nov 13, 2021 8:00 am | 26 ...

Sareum Holdings plc has announced the latest developments with its "Crystal Bank" resource of rapidly accessible protein structures first announced in September 2005. To date, Sareum has signed three ...

Protein crystals form in microgravity in the space station’s Kibo Module. Credits: JAXA For more than two decades, the International Space Station has provided a platform for growing and ...