Cytokines play a critical role as mediators of immune responses and are generated by a variety of cells. Methods that can be used to measure cytokine levels in a sample and differentiate between ...

Illustration depicting the mechanics behind flow cytometry—a technology that has revolutionized the fields of immunology and cell biology. Now, in the age of precision medicine, flow cytometry is ...

Development of techniques to more fully characterize T-cell responses will lead to a better fundamental understanding of T-cell effector and memory differentiation as well as function. Multiparameter ...

The ability to measure single-cell gene expression in complex samples, such as heterogeneous cancers or tissues undergoing an immune response, can lead to a better understanding of system-wide ...

Researchers from the University of Freiburg, Germany have developed a functional flow cytometry-based method for the diagnosis of innate primary immunodeficiencies (PIDs). The technique was applied to ...

T cells genetically engineered to express a lab-designed chimeric-antigen receptor, or CAR, offer many patients with blood cancer a new treatment option. But while these T cells may have lifesaving ...

Flow cytometry is and always has been a multiparametric technology. Increasingly simultaneous and correlated measurements can be used to provide greater detail about the phenotype of cellular ...

What are cell and gene therapies? Cell and gene therapies are used to treat, and sometimes cure, diseases by addressing the underlying genes or proteins. While there is overlap between the fields, ...

The Flow Cytometry and Cell Separation Facility provides advanced cell sorting and cell analysis techniques including immunofluorescence detection of 18 colors, cell-cycle distribution, apoptosis ...

CHICAGO — The use of a clinically validated flow cytometry test can assess type 1 and type 2 interferon activity in children with various pediatric inflammatory diseases to evaluate and monitor their ...