Dopamine’s effects in the brain are mediated by postsynaptic D1 and D2 receptors. Adenosine A1 and A2A receptors are uniquely positioned to counteract the excessive stimulation of dopamine receptors ...

the D1 receptors, which activate neurons, and the D2 receptors, which inhibit them. A third group of dopamine receptors that possess both D1 and D2 dopamine receptors was known to exist ...

1998). These five subtypes have been grouped into two different classes based on pharmacology and biochemistry: the D1-like and the D2-like receptors. The D1-like receptors, D1 and D5, mediate ...

This results in an increased D concentration in the synaptic cleft and activity of the D1 and D2 receptors.

and that both types of dopamine receptors, D1-like and D2-like, can mediate the increased infection. These data suggest that in macrophages, activation of both types of dopamine receptors triggers an ...

Altering the firing patterns of these dopamine pathways adjusted their social preferences, enhancing activity through D1 receptors to prefer females and shifting to D2 receptor-mediated signaling ...