Alogliptin (NESINA), a dipeptidyl peptidase IV (DPP-4) inhibitor, was approved by the FDA on January 25, 2013 to improve blood sugar control in adults with type 2 diabetes. This drug had been ...

Dipeptidyl peptidase-4 (DPP-4) inhibitors, commonly used to treat high blood glucose levels, have also shown efficacy against low blood sugar levels in a recent study. Menu SECTIONS.

DPP-4 inhibitors, compared with placebo or other treatments, were associated with a reduced risk of fractures (Mantel–Haenszel odds ratio [MH-OR] 0.60, 95% CI 0.37–0.99, P = 0.045), even after ...

Specifically, patients age 65 and older on a DPP-4 inhibitor saw a 62% higher risk for developing bullous pemphigoid compared with like-age sulfonylurea users (incidence rates 0.79 vs 0.49, HR 1. ...

Results showed that DPP-4 inhibitors yielded 0.42 cases of bullous pemphigoid per 1,000 person-years compared with 0.31 cases per 1,000 person-years for sulfonylureas (HR = 1.42; 95% CI, 1.17-1.72).

The combination of DPP-4 inhibitors and SGLT2 inhibitors resulted in higher direct medical costs but also increased total QALYs by 0.24. The incremental cost-effectiveness ratio for that pathway ...

(HealthDay News) — Dipeptidyl peptidase-4 (DPP-4) inhibitors are associated with increased risk of inflammatory bowel disease among patients with type 2 diabetes, according to a study published ...

1 Dipeptidyl peptidase-4 inhibitors are commonly used to treat diabetes, and are associated with development of noninflammatory bullous pemphigoid, with an incidence of 0.42 per 1000 person-years.1 – ...