Divalproex sodium 125mg; coated particles in caps. Increased risk of hepatotoxicity in patients with congenital metabolic disorders, multiple AEDs, severe seizure disorders with mental retardation ...

Objective: Divalproex extended release (ER) tablets have lower bioavailability than conventional divalproex tablets. Objectives were to provide dose-increment justification for conversion of a ...

Divalproex sodium 250mg, 500mg; ext-rel tabs. Increased risk of hepatotoxicity in patients with congenital metabolic disorders, multiple AEDs, severe seizure disorders with mental retardation ...

Divalproex ER has lower bioavailability than divalproex (divalproex ER/divalproex AUC ratio approximately 0.89). While switching patients from a divalproex to a divalproex ER regimen, the ...