When you have a dopamine deficiency, you may experience symptoms that can make it difficult to function. Low dopamine levels ...

Fixed and flexible doses of tavapadon significantly improved motor function compared with placebo in patients with Parkinson’s disease, according to a pair of phase 3 trials presented at the American ...

Nearly 16 million American adults have been diagnosed with attention deficit hyperactivity disorder (ADHD), but evidence ...

Recently, timed-release bromocriptine (Cycloset), a sympatholytic dopamine D 2 receptor agonist, has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of type 2 diabetes.

because they do not cause behavioral signs associated with activation of either normosensitive or supersensitive postsynaptic dopamine D 2 receptors (e.g., increased locomotion in reserpinized ...

“That, to me, is surprising and new and exciting.” Analyzing activity of dopamine receptors also reinforced the role this neurotransmitter plays in changing stages of sexual behavior. Miyasaka ...

For the first time, researchers have directly observed dopamine release in the human brain during moments of cognitive flexibility.

Dopamine’s effects in the brain are mediated by postsynaptic D1 and D2 receptors. Adenosine A1 and A2A receptors are uniquely positioned to counteract the excessive stimulation of dopamine receptors ...

At the neurotransmitter level, the dopamine system has been linked to cognitive flexibility ... Germany Eighteen participants were scanned with the D 2/3 receptor ligand 18 F-fallypride in a two-part ...

Scientists have confirmed a neurobiochemical link between dopamine and cognitive flexibility. PET imaging shows that the brain increases dopamine production when completing cognitively demanding tasks ...

Bromocriptine is unique in that it does not have a specific receptor that mediates its action on glucose and lipid metabolism. Rather, its effects are mediated via resetting of dopaminergic and ...