An ambispective, real-world multi-center study of DOstarlimab in patients with Recurrent or Advanced DNA mismatch repair deficient/microsatellite instability-high endometrial cancer (GEICO 120-R ...

Dostarlimab plus carboplatin significantly increased PFS among women with primary advanced or recurrent endometrial cancer, according to study results presented at Society of Gynecologic Oncology ...

Dostarlimab's approval represents "the first new frontline treatment option in decades" for patients with endometrial cancer, drugmaker GSK said in a press release.. Approval was based on interim ...

CHICAGO — Assessment of RUBY trial outcomes by blinded independent central review confirmed the benefits of adding dostarlimab to chemotherapy for women with primary advanced or recurrent ...

The US Food and Drug Administration (FDA) has expanded the approval of dostarlimab-gxly (Jemperli, GSK) in conjunction with carboplatin and paclitaxel, followed by single-agent dostarlimab-gxly ...

Recurrent endometrial cancer is cancer that returns after treatment, often in the pelvis, lymph nodes, ... Checkpoint inhibitors like dostarlimab (Jemperli) pembrolizumab ...

A study co-led by UCLA Health Jonsson Comprehensive Cancer Center investigators found that combining the immunotherapy drug dostarlimab with standard chemotherapy not only provides a meaningful ...

The FDA has approved a new drug for some adult patients with endometrial cancer. Jemperli (dostarlimably) — made by U.K. company GSK — is intended for primary advanced or recurrent disease.

Positive RUBY phase III data show potential for Jemperli (dostarlimab-gxly) combinations in more patients with primary advanced or recurrent endometrial cancer. News release. GSK.

Details of Dostarlimab Trial. The dostarlimab trial was conducted in 494 patients with primary advanced stage III or IV or first recurrent endometrial cancer who received first-line treatment with ...

Notably, dMMR, MSI-H tumors account for 25 to 30% of endometrial cancers. The approval of this new treatment option, which has shown promising results in the RUBY trial, can provide renewed hope for a ...

If you have a uterus and symptoms of endometrial cancer, your doctor will give you a physical exam. They may also order blood and urine tests to help them find out what’s going on. “The single ...