These inhibitors are typically small molecules designed by considering the structure of the active site or the substrate specificity of the enzyme. A common problem with small inhibitors ...

Inhibitors can be used to stop an enzyme from binding to its substrate. As a result, inhibitors can directly control the progress of a metabolic pathway.

This illustration depicts the process of enzyme catalysis. The enzyme (blue) binds to its substrate (red) to form an enzyme-substrate complex. The enzyme then catalyzes the conversion of the substrate ...