G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...

A recent study published in Nature by a research team from the United States and China introduced a new class of engineered G-protein-coupled receptors (GPCRs) called programmable antigen-gated ...

A new study in Engineering explores the role of astrocytic G protein-coupled receptors in drug addiction. It shows that these receptors, including ...

A new study, published today in Nature Chemistry by researchers from the University of Pittsburgh and Yale University, shows how common gut bacteria can metabolize certain oral medications that target ...

New findings on how the gut microbiome influences drug metabolism and effectiveness could open the door to personalized ...

Dr Morgan Li, Dr Alexandre Siqueira, Dr Sarah Piper, Dr Marcus Giansiracusa and Dr Laura Williams. Images supplied.Five ...

Structure Therapeutics Inc.’s GPCR share price has surged by 29.14%, which has investors questioning if this is right time to sell.

Title : Hemodynamic effects of TX45 , a long-acting Fc-relaxin fusion, in Group 2 pulmonary hypertension patients. Session : Late-breaking science in heart failure, cardiomyopathies, pulmonary ...

The proteins – large molecules that play many important roles in the body – help to relay information and are known GPCRs, or G protein-coupled receptors. Drugs that influence these proteins include ...