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For effective human-to-human transmission, genetic reassortment is needed for the virus to adapt to the human host. However, the virus is currently adapted to an avian host, not a mammalian one.
Only influenza A viruses infect nonhuman hosts, and a reassortment of genes can occur ... Although the basic biology and genetics of influenza viruses are fairly well understood, heading off ...
But the genetic lineage of the virus does offer ... and officials hypothesized that the reassortment of these genes occurred in pigs, said Nancy Cox, director of the CDC's Influenza Division.
That scenario is caused by “reassortment,” the exchange of genetic material when hosts are infected with multiple versions of a virus. The U.S. Agriculture Department’s Animal and Plant ...
In the present work, the idea of aneuploidy-catalyzed reassortment as the epigenetic ... As all of the cells studied have an otherwise identical genetic background, any differences in mutation ...
Pigs are the most important reservoir for influenza A viruses, acting as an intermediary host for both interspecies transmission and genetic reassortment. This is due to the high susceptibility of ...