If you’ve got room in your heart and home for large breed dogs, ... it wasn't until the early 1800s that they rose to prominence when the Duke of Gordon began breeding them at Gordon Castle.

The best large breed puppy food provides a complete and nutritious diet for your growing pet. Here are our top picks as vetted by a veterinarian. Newsletters Games Share a News Tip.

There are so many different types of large-breed dogs, so whether you're looking for a bouncing-off-the-walls buddy, calm companion, or go-with-the-flow friend, you'll almost certainly find the ...

“Giant breed dogs such as Great Danes, mastiffs, and Newfoundlands can continue to gain in height until age 2 or more. Large and giant breed dogs will continue to fill out even after they have ...

Choose the right large dog breed for you . Now that you know more about the most popular large dog breeds, it’s time to ...

Here are some of the largest dog breeds by weight and height: English Mastiff: 27.5-30 inches and up, 120-230 pounds Spanish Mastiff: 28-35 inches and up, 140-200 pounds Pyrenean Mastiff: 28-31 ...

LOY-001 reduces the levels of IGF-1 in large and giant dog breeds, extending healthy life spans. The drug is an injectable that would be administered by a vet every three to six months.