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Glucocorticoids are still one of the most commonly used treatments for rheumatoid arthritis, with an estimated up to 50% of patients with RA in the United States using them long-term as of 2021.
Glucocorticoid therapy is the most common cause of secondary osteoporosis and the leading iatrogenic cause of the disease. 1–3 Often, the presenting manifestation is fracture, which occurs in 30 ...
Janssens et al. conducted a randomized, double-blind, equivalence clinical trial to determine whether the glucocorticoid prednisolone can be used as an alternative to NSAIDs in this setting.
In patients with a rheumatic disease in whom glucocorticoid therapy was initiated at a daily dose of at least 7.5 mg of prednisone or the equivalent and who were treated for 18 months with ...
Glucocorticoid doses exceeding the equivalent of 40 mg prednisone daily are associated with a considerable risk of psychosis, particularly within the first 5 days of treatment. 82 Patients with ...
Moreover, in the glucocorticoid-continuing subpopulation, treatment with Prolia was associated with significant increases in lumbar spine BMD compared with active-control (3.8% vs 0.8%; treatment ...
Glucocorticoid tapering, education and treatment of adrenal crisis are three of the main focuses of a new clinical practice guideline on glucocorticoid-induced adrenal insufficiency. The Endocrine ...
Guidelines recommend minimizing glucocorticoid exposure in patients with lupus (SLE), and research suggests this advice should also apply to those with lupus nephritis.
The glucocorticoid dose at TMP-SMX discontinuation was significantly higher in patients with PJP than in those without the condition (median, 22.5 vs 10.0 mg prednisone-equivalent corticosteroids ...
Glucocorticoids are powerful medicines that fight inflammation and work with your immune system to treat wide range of health problems.. Your body actually makes its own glucocorticoids. These ...
Thus, the glucocorticoid receptor is a double-edged sword in prostate cancer. Due to it promoting the development of drug resistance in prostate cancer, it was shown to have oncogenic effects.