A surprising discovery about how brain cells handle sugar could shift how scientists approach dementia and Alzheimer’s treatments. In a new study published in Nature Metabolism, researchers uncovered ...

In a new study published in Nature Metabolism titled “Neuronal Glycogen Breakdown Mitigates Tauopathy via Pentose Phosphate Pathway-Mediated Oxidative Stress Reduction,” researchers from the Buck ...

Scientists found that glycogen, a stored sugar in brain cells, helps manage oxidative stress through its metabolism and may slow the progression of Alzheimer’s disease, according to a study published ...

New research published in Nature Metabolism has identified a previously underestimated contributor to tau-related neurodegenerative conditions, including Alzheimer’s disease and frontotemporal ...

Researchers have made a breakthrough discovery that solves a mystery long forgotten by science and have identified a potentially novel avenue in pre-clinical models to treat non-small cell lung ...

Researchers discover that glycogen and N-linked glycans accumulate in fibrotic regions of the lung and may be important for therapy development. Ramon Sun, a biochemist at the University of Florida ...

McArdle disease, also known as glycogen storage disease type V, is an inherited metabolic disorder marked by a deficiency of myophosphorylase, the enzyme essential for the breakdown of glycogen in ...

Scientists at the University of Kentucky Markey Cancer Center say they have made a discovery that solves a mystery and identified a potentially novel avenue in preclinical models to treat non-small ...

Optical densitometry (OD) of the cultures also indicated a dose-dependent rapid decrease in cell proliferation as revealed by the MTS assay (Figure 2). CP-320626 and 2-DOG-treated cultures showed ...