Mortality at 90-days was similar for early, goal-directed therapy patients (24.9 percent) and usual care patients (25.4 percent). 2. The adjusted odds ratio was 0.97.

After a single-center trial and observational studies suggesting that early, goal-directed therapy (EGDT) reduced mortality from septic shock, three multicenter trials (ProCESS, ARISE, and ProMISe) ...

Goal-directed therapy has been used for severe sepsis and septic shock in the intensive care unit. This approach involves adjustments of cardiac preload, afterload, and contractility to balance ...

Early, goal-directed therapy for septic shock – A patient-level meta-analysis. N Engl J Med . 21 March 2017. doi: 10.1056/NEJMoa1701380 From the May 01, 2017 Issue of Clinical Advisor ...

A team of doctors at Michigan Medicine have successfully treated a child in severe septic shock and multiorgan failure with ...

Early goal-directed therapy (EGDT) does not reduce 90-day mortality for patients presenting to the emergency department with early septic shock, according to a new study. Menu SECTIONS Home ...

Implementing early goal-directed therapy (EGDT) to improve outcomes in severe sepsis and septic shock has been slow due to barriers to its use. What are the economic challenges of implementing EGDT?

Early goal-directed therapy is a widely practiced approach for severe sepsis and septic shock, and fluid resuscitation within 6 hours is recommended (N Engl J Med. 2001;345:1368-1377).

Masimo announced a study comparing the performance of goal-directed fluid therapy (GDFT) using esophageal Doppler to GDFT using Masimo PVi®. Contacts Media Contact: Masimo Evan Lamb, 949-396-3376 ...

Principles and protocols for intravenous fluid therapy. We selected a randomised controlled trial by the ARISE Investigators and the ANZICS Clinical Trials Group (2014) for a full commentary because ...

This guideline covers the general principles for managing intravenous (IV) fluid therapy in hospital inpatients aged 16 and over with a range of conditions. It aims to help prescribers understand the ...