nevertheless, there was a small but statistically significant increase in major GI bleeding (47 [0.4%] vs 29 [0.2%]; p = 0.04) with high-dose versus low-dose aspirin.

Berger et al. retrospectively analyzed data from two trials of fibrinolytic therapy in STEMI to determine the effect of high-dose versus low-dose aspirin on cardiovascular outcome and bleeding events.

"Anyone who's not at a high risk of heart disease has to ... Talk to your doctor first. The standard dose is one baby aspirin (81 milligrams) a day. Higher doses are no more effective, and can ...

A new international clinical trial led by the National Cancer Center Singapore is reporting that three years of aspirin ...

For decades, taking low-dose aspirin every day was widely recommended as an easy way to prevent heart attacks and strokes. But that advice has changed.

Excretion of high-dose aspirin increased. Caution with diuretics, digoxin, aspirin in hypoprothrombinemia. Potentiated by oral contraceptives. Monitor oral anticoagulants.