The inaugural Hippo Pathway Targeted Drug Development ... the mechanistic understanding and potential of the Hippo signaling pathway to enhance the discovery, translation, and clinical development ...

This gene is part of the Hippo signaling pathway in the brain. It’s the first time a study associates it with human obesity. The authors found that reducing links in the pathway also ...

The interplay between hormone signaling and malignant transformation remains incompletely understood. This study identifies ...

In addition, many major signaling pathways were discovered in fruit flies, including the Hedgehog, Notch and Hippo pathways. In a new study, published in Developmental Cell, Monash University ...

These functions are regulated by the interplay of various signaling pathways. The TGF-β and HIPPO pathways are particularly relevant due to their roles in tumor suppression and liver regulation.

Delving deeper into the effects of SUMOylation, the researchers determined that it regulates a key protein in another well-known pathway, called Hippo. While the Hippo pathway is known to play a ...