A research group has identified the so-called PNOC/NPY nerve cells in the brains of mice. When activated, these cells ...

McGavock Professor and professor of molecular physiology ... may exert lasting effects on the structure and function of circuits that control energy balance. Leptin is a hormone that, in adults ...

Friedman’s laboratory at the Rockefeller University cloned the leptin gene in 1994. But now Bowen Tan, Kristina Hedbacker, and other researchers in Friedman’s Laboratory of Molecular Genetics ...

Here, we characterize two novel homozygous leptin variants that yielded antagonistic ... Details on protein structure modeling, activity, binding, internalization, and competition studies are ...

A single family has been described in which obesity results from a mutation in the leptin-receptor gene (LEPR), but the prevalence of such mutations in severe, early-onset obesity has not been ...

BOSTON – Leptin, a molecule linked with obesity, may play a crucial role in predicting poor prognosis from thyroid cancer, at least in the Middle Eastern region of the world, according to data ...

The new study shows that leptin toggles a runner’s desire by cutting access to a reward chemical — dopamine — in one of the brain’s motivation centers, the ventral tegmental area.

Friedman's laboratory at the Rockefeller University cloned the leptin gene in 1994. But now Bowen Tan, Kristina Hedbacker, and other researchers in Friedman's Laboratory of Molecular Genetics have ...