Nature

Interferon-β lipofection II. Mechanisms involved in cell death and bystander effect induced by cationic lipid-mediated interferon-β gene transfer to human tumor cells

We evaluated the cytotoxic effects (apoptosis, necrosis and early senescence) of human interferon-β (hIFNβ) gene lipofection. The cytotoxicity of hIFNβ gene lipofection resulted equivalent to that of ...
Nature

Lipofection of early passages of cell cultures derived from murine adenocarcinomas: In vitro and ex vivo testing of the thymidine kinase/ganciclovir system

Primary cultured cells, derived from P07 (lung), M3, M05, and M38 (mammary gland) murine adenocarcinomas were obtained by enzymatic digestion of tumor fragments with 0.01% Pronase (Sigma, St. Louis, ...
JSTOR Daily

Exposure of Human Ovarian Carcinoma to Cisplatin Transiently Sensitizes the Tumor Cells for Liposome-Mediated Gene Transfer

Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, No. 26 (Dec. 20, 1994), pp. 12669-12672 (4 pages) Human ovarian carcinoma cells (line 2008) grown as ...
EurekAlert!

Nanosurgery and the fight against cancer: Major breakthrough at Polytechnique Montréal

Montréal -- Researchers at Polytechnique Montréal have succeeded in changing the genetic material of cancer cells using a brand-new transfection method. This major breakthrough in nanosurgery opens ...
New Atlas

New CRISPR method edits crops without technically making them GMOs

CRISPR-Cas9 gene-editing is one of the most powerful tools available to modern science, but genetically-modified organisms (GMOs) in food are subject to some tight regulations. Now, researchers at ...