(A) Schematic diagram of the experimental system that detects calcium release from the endoplasmic reticulum by each ryanodine receptor. (B) Isoflurane selectively activates RyR1 (mean ± standard ...
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Discovery links RyR1 activation and calcium release to sedative effects of inhalational anesthetics
Since their effects were discovered approximately 180 years ago, inhalational anesthetics have been used for general anesthesia in surgical operations. However, the mechanism of their anesthetic ...
Since their anesthetic effects were discovered approximately 180 years ago, inhalational anesthetics have been used for general anesthesia in surgical operations. However, the mechanism of their ...
Wide-awake’ local anesthesia no tourniquet is noninferior to ultrasound-guided axillary block in patients undergoing carpal ...
Deaths from lidocaine poisonings more than doubled since 2010, calls to poison control centers suggested. Calls about local anesthetic poisonings decreased by 23%, mainly due to fewer non-lidocaine ...
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