Lysosomes are membrane-bound organelles whose acidic lumen (pH 4.5–5.0) is required for degradation. This luminal acidity is ...

Once thought of as having one simple job within cells, researchers continue to learn more about the importance of organelles called lysosomes. An organelle is a small structure in a cell that is ...

Therapeutic targeting of the AhR-Siglec-15 axis reveals potent efficacy against SHH medulloblastoma in preclinical models.

Lysosomes are membrane-bound organelles in cells that act as recycling centers—breaking down waste materials, damaged organelles, and unwanted molecules using powerful digestive enzymes. Lysosomes ...

CHICAGO (CBS) -- Lysosomes – membrane-bound structures within each cell of humans and all animals – are sometimes known as the cells' "garbage disposals" or "cellular janitors." The structures are ...

Transmission electron microscopic image of an isolate from the first U.S. case of COVID-19, formerly known as 2019-nCoV. The spherical viral particles, colorized blue, contain cross-section through ...

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, report in Nature Communications on how the targeted suppression of lysosome function may lead to brain cancer therapy.

New research shows the use of a new cellular probe helped discover new findings about certain cellular processes. Collaborative research at the University of Cincinnati has developed a new probe to ...

This article and associated images are based on a poster originally authored by Teresa Sorbo, Manuel Paina, Manuel Arcangeletti, Katja Blasi, Sara Martin, Donatella Bardelli, Paola Picardi, Fernanda ...

Knowing which lysosomal proteins are enriched in which brain cell types will help better understand contribution to neurological disorders.