A new study reveals how the Dnmt3a mutation drives blood stem cell overgrowth, contributing to clonal hematopoiesis and ...

Mitochondria play a crucial role in acquiring pluripotency and determining cell fate. The mitochondrial unfolded protein ...

We wanted to determine what happens to the cell when the lysosomes are not functioning well or are overwhelmed, and if there was another pathway to temporarily deal with the damaged mitochondria. This ...

Metformin exerts its glucose-lowering effects by disrupting energy production within the mitochondria, a key organelle ...

initiated by either the mitochondria (the 'intrinsic' pathway) or the cell surface receptors (the 'extrinsic' pathway). Mitochondria-mediated apoptosis occurs in response to a wide range of death ...

As we age, blood stem cells, the essential source of new blood cells in the body, can accumulate genetic mutations. These ...

elegans mitochondrial factor WAH-1 promotes phosphatidylserine ... Caenorhabditis elegans drp-1 and fis-2 Regulate Distinct Cell-Death Execution Pathways Downstream of ced-3 and Independent of ced-9 ...