Although using misoprostol without mifepristone is off-label and not approved by the FDA, OB-GYNs and abortion rights advocates are saying that it is, in fact, a safe way to induce an abortion.

If mifepristone loses FDA approval, clinicians who provide abortions will be able to offer either surgical abortions or misoprostol-only abortions, but the new regimen will include extra training ...

Officials say California currently has more than 250,000 of the pills already on hand, which were purchased for about $100,000. That's enough pills to cover an estimated 12,000 misoprostol-only ...

Mifepristone was approved more than 20 years ago to induce first-trimester abortions in combination with a second drug, misoprostol. Image: Charlie Neibergall/AP ...

Washington ordered an additional 17,600 doses of mifepristone and 61,500 of misoprostol in January 2025 because an initial order expires early next year, a spokesperson said.

Health officials are reviewing a dubious report that claims dangerous complications from mifepristone. ... United States and typically involves the drugs mifepristone and misoprostol (Getty Images) ...

The birth control ingredient name-dropped in Project 2025 is suddenly getting new attention, thanks to research suggesting it could serve as a mifepristone substitute.

Reproductive-rights advocates are pushing back against the review of the abortion medication mifepristone ordered by Health and Human Services (HHS) Secretary Robert F. Kennedy Jr.

In 2023, he ordered the state to stock up on another abortion drug, misoprostol, that is slightly less effective than when it is taken in combination with mifopristone.

Mifepristone and misoprostol together Typically, to either induce an abortion or help manage an early miscarriage, mifepristone is taken first. It's been approved by the FDA since 2000.