Scientists at St. Jude Children's Research Hospital have created a database that provides updated predicted structures on a ...

Researchers have detailed PEPPI-MS, an experimental protocol combining high-resolution protein fractionation using SDS-polyacrylamide gel electrophoresis (SDS-PAGE) with the latest mass spectrometry ...

Proteins are strikingly complex macromolecules, which control every aspect of molecular function in all living organisms, making them an interesting research target. The Ando Lab studies the structure ...

Efforts to unlock the mysteries of proteins, building blocks of life, have earned three scientists the 2024 Nobel Prize in chemistry. The prize goes to David Baker “for computational protein design,” ...

When a protein folds, its string of amino acids wiggles and jiggles through countless conformations before it forms a fully folded, functional protein. This rapid and complex process is hard to ...

A team led by UT Southwestern Medical Center researchers has uncovered the atomic structure of a protein complex pivotal to the function of motile cilia, the hair-like structures extending from the ...

Inside every cell, a finely tuned metabolic network determines when to build, recycle, or stop producing essential molecules.

Researchers have discovered that the enzyme NUDT5 utilizes its structure to exercise metabolic control over a key pathway in ...

For decades, scientists have known that motor proteins like kinesin-2 ferry vital cargo along microtubule "highways" inside ...