Communication between oocytes and granulosa cells is essential for oocyte formation, dormancy, reawakening, and maturation. Researchers have demonstrated that a protein complex called the exocyst ...
In a new study published in the journal Nature, researchers in Japan report that activating just eight genes for producing gene-controlling proteins is enough to convert mouse stem cells directly into ...
When the female germline develops, oocyte growth is accompanied by many changes in gene expression, however, the regulatory networks that control this process have not been determined. Now, a group of ...
This photo shows a mouse obtained from gPSC4-derived oocytes by IVM and IVF. The mouse is now about one year old. The gPSC4- mice have reproductive ability and produced 13 and 7 pups, respectively, ...
Oocytes are immature egg cells that develop in almost all female mammals before birth. The propagation of future generations depends on this finite reserve of cells surviving for many years without ...
Mechanistic model for MTOC maturation in GV oocytes. The MTOC (grey) activates near the oocyte cortex, which requires recruitment of CKAP5 and TACC3. After activation, MTOC migrates to the nuclear ...
In a new study published in the journal Nature, researchers in Japan report that activating just eight genes for producing gene-controlling proteins is enough to convert mouse stem cells directly into ...
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