SOX17 mutations are linked to severe pulmonary arterial hypertension often diagnosed in childhood, though some develop the ...

Scientists have created a new technique that can assess how mutations in the genome influence the packaging of DNA in cells. The genome is massive, and has to be carefully wrapped around proteins so ...

Some genetic mutations that are expected to completely stop a gene from working surprisingly cause only mild or even no symptoms. Researchers in previous studies have discovered one reason why: cells ...

Researchers from the HUN-REN Szeged Biological Research Centre and HCEMM have just published a new study suggesting that it's not simply the number of tumor mutations that matters for immunotherapy, ...

The story of Chernobyl has long carried a chilling epilogue: that the people who rushed in to contain the disaster doomed not only themselves, but their children, to hidden genetic damage. The ...

A graph-based computational tool for detecting previously invisible genetic mutations has been developed. Researchers at the University of California, Los Angeles (UCLA; USA) and the University of ...

A new long-read sequencing technique has helped researchers investigate how DNA mutations arise in a variety of contexts. A collaboration of researchers led by NYU Langone Health and NYU Grossman ...

Our DNA is compacted and arranged into chromosomes, most of which are shaped like X’s. The ends of the chromosomes' arms are protected with caps known as telomeres. Telomeres are made up of highly ...

Cancer is often thought of as a single disease, but at the genetic level, tumours arising in the same organ can behave in ...