Oligodendrocytes (OLs) differentiate to myelinate central nervous system (CNS). CNS myelination by OLs is important not only for saltatory conduction of action potentials but also for trophic support ...

Osteocalcin (OCN) is a multifunctional bone-derived hormone that modulates numerous physiological activities. OCN can cross the blood brain barrier (BBB) and thus play critical roles in neuronal and ...

The human brain remains adaptable even into adulthood alternately strengthening and weakening various neural pathways. And now, new research from Stanford Medicine scientists suggests that this ...

Scientists have found that the process of adaptive myelination, which helps the brain learn new skills, can also promote addiction to opioids. Our brains, even in adulthood, continually adapt to what ...

Scientists have shown in both anxious rats and military veterans with PTSD that acute stress is associated with increased myelination of axons in areas of the brain associated with memory and emotions ...

Osteocalcin (OCN) is a multifunctional bone-derived hormone that modulates numerous physiological activities. OCN can cross the blood brain barrier (BBB) and thus play critical roles in neuronal and ...

Researchers at Institute of Science Tokyo have identified laminin-411 and A4G47, a synthetic peptide derived from the E8 domain of laminin-411 protein, as the key factors in the maturation of ...

It’s not so easy being an adolescent these days. We become aware of the world around us, are flooded with input through digital media about our extended global family, and learn about the world’s ...

Black gold staining in postmortem human brain samples from three individuals reveals significantly less myelination in people carrying a copy of the APOE4 Alzheimer's disease risk gene. [Tsai ...

Amino acids are essential for cell growth and metabolism. Amino acid and growth factor signaling pathways coordinately regulate the mechanistic target of rapamycin complex 1 (mTORC1) kinase in cell ...