Natural Human Protein Reactivates Dormant HIV, Bringing Scientists One Step Closer to a Cure

A natural vitamin A transporter, RBP4, can awaken latent HIV through NF-κB signalling, offering a new angle for cure ...
Nature

Stepwise phosphorylation of p65 promotes NF-κB activation and NK cell responses during target cell recognition

NF-κB is a key transcription factor that dictates the outcome of diverse immune responses. How NF-κB is regulated by multiple activating receptors that are engaged during natural killer (NK)-target ...
Nature

Ubiquitin signalling in the NF-κB pathway

NF-κB is a dimeric transcription factor that consists of REL family members, including REL-A (also known as p65), c-REL, REL-B, p50 and p52 (ref. 14). p50 and p52 are derived from the larger ...