Retinitis pigmentosa (RP) is a genetic eye disorder affecting around one in 5,000 people worldwide. It typically begins with ...

Non-coding DNA is essential for both humans and trypanosomes, despite the large evolutionary divergence between these two species.

Rapid advances in sequencing technologies have transformed our ability to diagnose human genetic disorders, yet many patients still lack a molecular ...

In patients with retinitis pigmentosa (RP), crucial cells in the retina known as rods and cones die over time; night ...

In RNA molecules, the 5′ untranslated region (UTR) is located directly upstream of the start codon and plays a crucial role in post-transcriptional regulation by controlling RNA stability, cellular ...

Sequencing nearly half a million genomes, researchers show that most additive genetic influences on height, lipids, and other complex traits are now directly measurable, while pinpointing ultra-rare ...

The non-coding genome, once referred to as "junk DNA," is now understood to be a fundamental regulator of gene expression and a key factor in understanding complex diseases. Image credit: ...

Each cell in the body is like a miniscule bowl of genetic soup, holding RNA from thousands of genes. But unlike an actual bowl of soup, which can forgive a little too much or not enough of certain ...

A new study details the discovery of rare gene variants that increase the prevalence of Type 2 diabetes in multiple generations of Asian Indian people. The unusual finding is a step toward more ...

Dharambir Sanghera, Ph.D., is a professor of pediatric genetics at the University of Oklahoma College of Medicine. “We wanted to study several generations of Asian Indians because understanding ...