It has been known for several years that abnormal chromosome numbers lead to protein imbalances in the affected cells.

In this case, the team didn’t sequence an X chromosome from a normal human cell. Instead, they studied a special type of cell that contains two identical chromosomes, part of a model genome ...

The normal human chromosome contains 23 pairs of chromosomes, giving a total of 46 chromosomes in each cell, called diploid cells. A normal sperm or egg cell contains only one half of these pairs ...

The human genetic blueprint is deceptively simple. Our genes are tightly wound into 46 X-shaped structures called chromosomes. Crafted by evolution, they carry DNA and replicate when cells divide, ...

In the cells with 45 chromosomes, the presence of 15 chromosomes in the size range of 6 to 12 plus X, and only two pairs in the 21, 22 range indicate an XO sex-chromosome constitution.

Scientists found that healthy women can carry genetic changes in their breast cells that are thought to be characteristic of ...

Some of the most harmful genetic changes in cancer are also the hardest to see. These structural alterations, deep within a ...

Normal gene expression in cells also requires many local and distant regulatory factors, which are virtually impossible to reproduce artificially outside of a chromosome-like context. Moreover, ...

Stock image of a human chromosome. A yeast chromosome has been synthesized from scratch for the very first time. ISTOCK / GETTY IMAGES PLUS. This research may also one day be applicable to humans ...

This complete Y chromosome has 106 protein-coding genes, which is 41 more than in the reference genome. But almost all these extra genes are just copies of one gene called TSPY.. At the same time ...