Glucocerebrosidase was purified 26,000-fold from spleens from normal humans and from patients with Gaucher disease (Gaucher spleens). The specific activities of the purified normal and mutant enzymes ...

THE recent independent observation, by several of us, of peculiar histiocytosis of the spleens of patients with "idiopathic" thrombocytopenic purpura has prompted the collection and review of the ...

Image of B lymphocytes (in blue) surrounded by neutrophils (in green) and endothelial cells (in red) of a human spleen. The image on the left side corresponds to a normal spleen and on the right side ...

Splenomegaly is one of the characteristic signs of an overactive spleen. It can cause platelets to pool inside of your spleen and cause thrombocytopenia. Thrombocytopenia is when you have a low ...

RUPTURE of the spleen, a frequent acute abdominal condition characterized by symptoms and signs of internal hemorrhage and shock, necessitates surgical intervention, usually splenectomy. In a typical ...

In order to assess how the MR/CR ligand system may function across species, we have generated a chimaeric protein containing the human CR fused to mouse IgG2a Fc to investigate the presence of CR ...

Addition of normal C57BL/6 mouse bone marrow cells to an in vitro culture of normal C57BL/6 spleen cells and allogeneic P815-Y tumor cells inhibited the development of cell-mediated immunity. Bacillus ...