A structure for nucleic acid has already been proposed by Pauling ... We have made the usual chemical assumptions, namely, that each chain consists of phosphate di-ester groups joining p-D-deoxy ...

Our research focuses on all aspects of nucleic acid structure, chemistry and function employing state of the art technologies and approaches. The structure and chemistry of nucleic acids is ...

RNA is usually single-stranded but can form complex secondary structures through ... develop new crop varieties. Nucleic acid-based techniques, such as polymerase chain reaction (PCR) and DNA ...

"We've essentially been watching life's machinery in action at the molecular level," Professor Bond said. "By visualizing how these complex structures assemble and ... binding by a designer PPR ...

alongside Molecular Dynamics (MD) simulations. These studies, combined with structural diversity data from the Protein Data Bank (PDB), provide a foundation for developing predictive models linking ...

Unlike antibodies, aptamers' unique structures include hairpin regions (red), which provide stability. The image also highlights chemical modifications (yellow) that increase durability, and biotin ...

In a perspective, Northwestern Engineering’s Chad Mirkin and Milan Mrksich argue that structural precision drives therapeutic ...

WEST LAFAYETTE, Ind. — A researcher in Purdue University’s College of Science is developing a patent-pending platform technology that mimics the dual-layer structure of viruses to deliver nucleic acid ...

This webinar will explore the most recent ASO chemical modification: locked nucleic acid (LNA), which confers high potency. Our expert speakers will provide insights into the critical in vitro and in ...