The San Francisco 49ers were thought to be among the favorites to represent the NFC in the Super Bowl for a second straight year, but they haven't ...

Women of the Niners' were treated to an evening of painting the 49ers 75th Anniversary logo and enjoying wine from The Federalist. WON Paint Night Presented by The Federalist WON Members were ...

After swapping his cleats for a microphone, the spotlight during Sunday's game between the San Francisco 49ers and Arizona ...

The NFL denied the San Francisco 49ers' request to change to an all-white uniform set before the hottest game in Levi's ...

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Rob Gronkowski told Fox News Digital there’s only one question the 49ers have left to answer this season. "I believe the San Francisco 49ers now have the best team on paper in the NFL ...

George Kittle is listed as questionable as he heads into the San Francisco 49ers' Week 5 matchup with the Arizona Cardinals. The matchup begins at 4:05 PM ET on Sunday. All of Kittle's numbers ...

The San Francisco 49ers apparently came extremely close to trading Brandon Aiyuk to the Pittsburgh Steelers. The team was actually on the phone with the Steelers when Aiyuk arrived at the 49ers ...

The San Francisco 49ers will be without star running back Christian McCaffrey for a while. The 49ers are placing McCaffrey on injured reserve, a person familiar with the situation told USA TODAY ...

McCaffrey is a do-it-all back that gives defenses fits. The 49ers have talent all over their offense but it starts with McCaffrey. He rushed for 1,459 yards and 14 touchdowns last season and had ...

Minnesota Vikings wide receiver Justin Jefferson's 97-yard touchdown reception in the Vikings' 23-17 win over the San Francisco 49ers was the longest scoring play of Week 2 through Sunday.