Scientists have identified a new mechanism that impacts tumor growth. The typical lack of oxygen in tumors doesn't only stimulate proliferation, but also offsets the important role of the protein PHD2 ...
The rapid growth of tumours results in their surpassing the capacity of the established circulatory system to supply the developing tumour with oxygen and nutrients as well as remove waste products.
STANFORD, Calif. — Tumors need a healthy supply of blood to grow and spread. Researchers at the Stanford University School of Medicine have identified a molecule that regulates blood vessel growth ...
New research suggests a counterintuitive new method to make cancer less likely to spread: by normalizing the shape of tumors' blood vessels to improve their oxygen supply. Such a treatment strategy ...
It was recently reported that a PPARα/γ agonist elevated pyruvate dehydrogenase kinase isozyme 4 (PDK4) mRNA levels in liver compared with vehicle or a PPARγ agonist [42]. In the present study, we ...
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