"And we're not used to having somebody without a career at stake in the room at a senior level," said Hudson.

Overall, prasugrel may be superior to the approved dose of the older drug, clopidogrel (Plavix), in many cases. But more doctors have been using an initial, higher-than-standard dose of ...

Dr. Sabatine: Clopidogrel is a prodrug and it needs to be activated through sequential oxidative steps in the liver (Slide 1). There is another pathway where esterases can take that pro-drug and ...

FDA-approved indications currently recommend that patients who undergo percutaneous intervention with drug-eluting stents (DESs) should be treated with clopidogrel for 3–6 months; however ...